Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365441 | 1.00 | LMNA (0.54) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365369 | 0.90 | ALDH1A1 (0.68) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365375 | 0.90 | ALDH1A1 (0.68) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365675 | 0.87 | LMNA (0.53) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365679 | 0.87 | LMNA (0.53) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9366482 | 0.86 | LMNA (0.52) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9366481 | 0.86 | LMNA (0.52) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9366567 | 0.86 | LMNA (0.52) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365487 | 0.84 | KMT2A (0.48) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9366552 | 0.84 | ALDH1A1 (0.48) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |