Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | ACKR3 | P25106 | 9/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20268270 | 0.85 | CES2 (0.53) | CES2CES1ACKR3DRD2NPC1 | |
| SCHEMBL11847285 | 0.81 | CES2 (0.57) | CES2CES1ACKR3DRD2NPC1 | |
| SCHEMBL13193363 | 0.79 | CTNNB1 (0.51) | CES2CES1 | |
| SCHEMBL3527017 | 0.77 | CES2 (0.57) | CES2CES1ACKR3DRD2 | |
| SCHEMBL31661842 | 0.77 | CES2 (0.57) | CES2CES1ACKR3DRD2 | |
| SCHEMBL6944180 | 0.77 | CES2 (0.57) | CES2CES1ACKR3 | |
| SCHEMBL959448 | 0.77 | CES2 (0.57) | CES2CES1ACKR3DRD2NPC1 | |
| SCHEMBL2832589 | 0.76 | RAB9A (0.49) | CES2CES1NPC1RAB9AL3MBTL1 | |
| SCHEMBL29145581 | 0.76 | CES2 (0.47) | CES2CES1ACKR3L3MBTL1 | |
| Ethylene SCHEMBL10996445 | 0.75 | CES2 (0.50) | CES2CES1ACKR3DRD2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318214-B1 | Tri- and tetra-substituted-oxetanes and -tetrahydrofurans and intermediates thereof | SCHERING CORP (US) | 1994-12-14 | — | — | EP | disclosed |
| US-5039676-A | Fungicide, antiallergens | SCHERING CORPORATION (US) | 1991-08-13 | — | — | US | disclosed |
| EP-0386143-A1 | TRI- AND TETRA-SUBSTITUTED-OXETANES AND TETRAHYDROFURANS AND INTERMEDIATES THEREOF | SCHERING CORPORATION (US) | 1990-09-12 | — | — | EP | disclosed |
| WO-1989004829-A1 | TRI- AND TETRA-SUBSTITUTED-OXETANES AND TETRAHYDROFURANS AND INTERMEDIATES THEREOF | SCHERING CORPORATION (US) | 1989-06-01 | — | — | WO | disclosed |
| EP-0318214-A1 | Tri- and tetra-substituted-oxetanes and -tetrahydrofurans and intermediates thereof | SCHERING CORPORATION (US) | 1989-05-31 | — | — | EP | disclosed |