Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365701 | 0.85 | LMNA (0.79) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9365369 | 0.76 | ALDH1A1 (0.68) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9366481 | 0.75 | LMNA (0.52) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9366567 | 0.75 | LMNA (0.52) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9366482 | 0.75 | LMNA (0.52) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9365679 | 0.75 | LMNA (0.53) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9369302 | 0.73 | LMNA (0.78) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9365441 | 0.72 | LMNA (0.54) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9366552 | 0.72 | ALDH1A1 (0.48) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8342494 | 0.71 | LMNA (0.75) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |