Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621847 | 0.85 | L3MBTL1 (0.41) | L3MBTL1HRH1LMNAHRH3HRH4 | |
| SCHEMBL166483 | 0.83 | PARP10 (0.48) | L3MBTL1HRH1LMNAPARP10ALDH1A1 | |
| SCHEMBL29818128 | 0.83 | PARP10 (0.48) | L3MBTL1HRH1LMNAPARP10ALDH1A1 | |
| SCHEMBL11833416 | 0.78 | ALDH1A1 (0.53) | L3MBTL1LMNAALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL28343693 | 0.78 | L3MBTL1 (0.53) | L3MBTL1HRH1LMNAHRH3HRH4 | |
| 2-Aminopyridine SCHEMBL9282249 | 0.77 | NOS3 (0.46) | L3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| Benzamide SCHEMBL18171705 | 0.77 | PARP10 (0.52) | L3MBTL1LMNAPARP10ALDH1A1SMN1; SMN2 | |
| SCHEMBL6093499 | 0.75 | AURKA (0.46) | L3MBTL1LMNAPARP10ALDH1A1SMN1; SMN2 | |
| SCHEMBL28310418 | 0.75 | AURKA (0.46) | L3MBTL1LMNAPARP10ALDH1A1SMN1; SMN2 | |
| SCHEMBL5792277 | 0.75 | AURKA (0.46) | L3MBTL1LMNAPARP10ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427161-B1 | Picolylselenobenzamides of aminopyridines, anilines and picolylamines | NATTERMANN A & CIE (DE) | 1994-04-20 | — | — | EP | claimed |
| EP-0427161-A1 | Picolylselenobenzamides of aminopyridines, anilines and picolylamines | A. Nattermann & Cie. GmbH (DE) | 1991-05-15 | — | — | EP | claimed |
| EP-0427161-B1 | Picolylselenobenzamides of aminopyridines, anilines and picolylamines | NATTERMANN A & CIE (DE) | 1994-04-20 | — | — | EP | disclosed |
| EP-0427161-B1 | Picolylselenobenzamides of aminopyridines, anilines and picolylamines | NATTERMANN A & CIE (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-5126357-A | ANTI-INFLAMMATORY PICOLYSELENOBENZAMIDES AND SALTS THEREOF | A. NATTERMANN & CIE. GMBH (DE) | 1992-06-30 | — | — | US | disclosed |
| EP-0427161-A1 | Picolylselenobenzamides of aminopyridines, anilines and picolylamines | A. Nattermann & Cie. GmbH (DE) | 1991-05-15 | — | — | EP | disclosed |
| EP-0427161-A1 | Picolylselenobenzamides of aminopyridines, anilines and picolylamines | A. Nattermann & Cie. GmbH (DE) | 1991-05-15 | — | — | EP | disclosed |
| EP-0427161-A1 | Picolylselenobenzamides of aminopyridines, anilines and picolylamines | A. Nattermann & Cie. GmbH (DE) | 1991-05-15 | — | — | EP | disclosed |