Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 5/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499786 | 0.87 | KMT2A (0.46) | MRGPRX1SMN1; SMN2KMT2AJAK1CCR2 | |
| SCHEMBL9363911 | 0.86 | IDH2 (0.41) | MRGPRX1LMNACA12CA2CA7 | |
| SCHEMBL9364420 | 0.84 | CA12 (0.38) | MRGPRX1MITFS1PR4LMNAHPGD | |
| SCHEMBL9502941 | 0.82 | GAA (0.40) | MRGPRX1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL9499704 | 0.81 | ULK1 (0.37) | MRGPRX1LMNAHPGDSTAT1HTT | |
| SCHEMBL9368768 | 0.81 | NPC1 (0.40) | MRGPRX1S1PR4LMNAHPGDS1PR1 | |
| SCHEMBL9368626 | 0.80 | IDH2 (0.40) | MRGPRX1HTTCA12CA2CA7 | |
| SCHEMBL9363636 | 0.79 | KMT2A (0.37) | MRGPRX1HTTSMN1; SMN2KMT2ACCR2 | |
| SCHEMBL9364278 | 0.79 | IDH2 (0.39) | MRGPRX1LMNAHTTNPSR1CA12 | |
| SCHEMBL9501500 | 0.78 | EPHX2 (0.38) | MRGPRX1HTTKMT2AJAK1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447013-B1 | Fluorobenzene sulphonamides | SCHERING AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |
| EP-0447013-A1 | Fluorobenzene sulphonamides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |