Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368768 | 0.92 | NPC1 (0.40) | MRGPRX1KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL9499710 | 0.89 | KMT2A (0.45) | GAAMRGPRX1KDM4EALDH1A1KMT2A | |
| SCHEMBL9368626 | 0.86 | IDH2 (0.40) | MRGPRX1ALDH1A1KMT2AHTTBRAF | |
| SCHEMBL9501500 | 0.84 | EPHX2 (0.38) | MRGPRX1ALDH1A1KMT2AHTTEPHX2 | |
| SCHEMBL9363404 | 0.82 | KMT2A (0.42) | MRGPRX1KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL9367203 | 0.82 | MRGPRX1 (0.42) | MRGPRX1ALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL9501345 | 0.81 | EPHX2 (0.37) | MRGPRX1KDM4EALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9364278 | 0.81 | IDH2 (0.39) | GAAMRGPRX1ALDH1A1KMT2ALMNA | |
| SCHEMBL9364420 | 0.79 | CA12 (0.38) | MRGPRX1KDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL9499704 | 0.78 | ULK1 (0.37) | MRGPRX1KDM4EKMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |