Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502967 | 0.90 | KMT2A (0.43) | EPHX2PPARGMRGPRX1ARTRPV1 | |
| SCHEMBL9501345 | 0.89 | EPHX2 (0.37) | EPHX2PPARGMRGPRX1ARJAK1 | |
| SCHEMBL9363636 | 0.88 | KMT2A (0.37) | EPHX2PPARGMRGPRX1ARKMT2A | |
| SCHEMBL9502941 | 0.84 | GAA (0.40) | EPHX2PPARGMRGPRX1JAK1KMT2A | |
| SCHEMBL9499704 | 0.83 | ULK1 (0.37) | MRGPRX1ARKMT2ABRAFHTT | |
| SCHEMBL9368768 | 0.82 | NPC1 (0.40) | EPHX2PPARGMRGPRX1ARJAK1 | |
| SCHEMBL9364420 | 0.81 | CA12 (0.38) | MRGPRX1ARKMT2ABRAFHTT | |
| SCHEMBL9367139 | 0.81 | KMT2A (0.35) | EPHX2PPARGMRGPRX1ARKMT2A | |
| SCHEMBL9363829 | 0.80 | IDH2 (0.41) | MRGPRX1KMT2ABRAFIDH2 | |
| SCHEMBL9501405 | 0.79 | KMT2A (0.41) | EPHX2PPARGMRGPRX1ARKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |