Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342461 | 0.86 | HRH3 (0.44) | HRH3CXCR3ITGB3ITGA2BNPC1 | |
| SCHEMBL7342470 | 0.86 | HRH3 (0.44) | HRH3CXCR3ITGB3ITGA2BNPC1 | |
| SCHEMBL7346577 | 0.75 | ITGB3 (0.52) | HRH3CXCR3ITGB3ITGA2BALOX15 | |
| SCHEMBL7346169 | 0.74 | UBE2T (0.43) | HRH3ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL9367388 | 0.73 | ITGB3 (0.49) | HRH3CXCR3ITGB3ITGA2BGAA | |
| Trifluoroacetic Acid SCHEMBL7344932 | 0.72 | ITGB3 (0.49) | HRH3CXCR3ITGB3ITGA2BALOX15 | |
| SCHEMBL7345703 | 0.72 | ITGB3 (0.71) | HRH3CXCR3ITGB3ITGA2BALOX15 | |
| SCHEMBL7339480 | 0.71 | ITGB3 (0.50) | HRH3CXCR3ITGB3ITGA2BALOX15 | |
| SCHEMBL7338379 | 0.71 | ITGB3 (0.54) | HRH3ITGB3ITGA2BALOX15 | |
| SCHEMBL7338384 | 0.71 | ITGB3 (0.54) | HRH3ITGB3ITGA2BALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612313-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993010091-A2 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |