Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 6/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353174 | 0.86 | F2 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7346164 | 0.84 | UBE2T (0.44) | UBE2TRETOPRM1OPRK1ITGB3 | |
| SCHEMBL7381654 | 0.82 | UBE2T (0.51) | UBE2TOPRM1OPRK1ITGB3ITGA2B | |
| SCHEMBL9367305 | 0.74 | HRH3 (0.43) | HRH3ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL7355673 | 0.73 | SMN1; SMN2 (0.46) | KMT2A | |
| SCHEMBL7356492 | 0.73 | F2 (0.52) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949253 | 0.71 | NPC1 (0.45) | ITGB3ITGA2BNPC1RAB9AKMT2A | |
| SCHEMBL7352886 | 0.70 | ITGB3 (0.49) | ITGB3ITGA2BNPC1RAB9AKMT2A | |
| SCHEMBL9371212 | 0.70 | ITGB3 (0.50) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949247 | 0.69 | KDM1A (0.44) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637304-A1 | 1-PIPERAZINEACETIC DERIVATIVES AS FIBRINOGEN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993022303-A1 | 1-PIPERAZINEACETIC DERIVATIVES AS FIBRINOGEN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1993-11-11 | — | — | WO | disclosed |