Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368291 | 0.93 | KDM4E (0.60) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL25960 | 0.84 | ALDH1A1 (0.47) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL29516909 | 0.84 | ALDH1A1 (0.47) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL9337870 | 0.82 | MAPK1 (0.48) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL9337864 | 0.81 | ACHE (0.49) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL9373443 | 0.79 | ACHE (0.57) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL12964716 | 0.78 | KDM4E (0.83) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL9373450 | 0.78 | KDM4E (0.43) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL9368249 | 0.77 | NPC1 (0.45) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL9686677 | 0.76 | MAPK1 (0.61) | NPC1RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332043-B1 | Oxadiazole derivatives containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them | HOECHST AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| US-5216158-A | Oxadiazole compounds containing 4,6-bis-trichloromethyl-S-triazin-2-yl groups, process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0332043-A1 | Oxadiazole derivatives containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-13 | — | — | EP | disclosed |