Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799821 | 0.87 | TDP1 (0.62) | TDP1ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL13721530 | 0.87 | TDP1 (0.57) | TDP1ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL3840814 | 0.84 | TDP1 (0.48) | TDP1ALDH1A1MAPK1MAPTTSHR | |
| SCHEMBL34473595 | 0.82 | TDP1 (0.47) | TDP1ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL34472553 | 0.82 | TDP1 (0.47) | TDP1ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL29091577 | 0.82 | TDP1 (0.47) | TDP1ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL6576154 | 0.80 | TDP1 (0.53) | TDP1ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL3839293 | 0.80 | ALDH1A1 (0.49) | TDP1ALDH1A1MAPTLMNAMERTK | |
| SCHEMBL19783654 | 0.79 | TDP1 (0.52) | TDP1ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL15538632 | 0.78 | VCAM1 (0.47) | TDP1ALDH1A1MAPK1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454329-B1 | FLUORESCENT DYES AND USES THEREOF | BECKMAN COULTER INC (US) | 2018-04-18 | — | — | EP | disclosed |
| US-8772501-B2 | Fluorescent dyes and uses thereof | BECKMAN COULTER, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130131324-A1 | Novel Fluorescent Dyes and Uses Thereof | BECKMAN COULTER, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-8367842-B2 | Fluorescent dyes and uses thereof | BECKMAN COULTER, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| EP-2454329-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | Beckman Coulter, Inc. (US) | 2012-05-23 | — | — | EP | disclosed |
| US-20110014599-A1 | Novel Fluorescent Dyes and Uses Thereof | BECKMAN COULTER, INC. (US) | 2011-01-20 | — | — | US | disclosed |
| WO-2011008912-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | BECKMAN COULTER, INC. (US) | 2011-01-20 | — | — | WO | disclosed |
| EP-0034945-B1 | N-PHENYLPYRAZOLE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1985-08-07 | — | — | EP | disclosed |
| US-4496390-A | WEED-CONTRTOLLING HERBICIDES | MAY & BAKER LIMITED (GB) | 1985-01-29 | — | — | US | disclosed |
| EP-0034945-A2 | N-phenylpyrazole derivatives | MAY & BAKER LIMITED (GB) | 1981-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131324-A1 | Novel Fluorescent Dyes and Uses Thereof | GUSB, CHLSN, NQO1 | TDP1 2019/4885ALDH1A1 480/4885MAPK1 4867/4885 |
| US-20110014599-A1 | Novel Fluorescent Dyes and Uses Thereof | GUSB, CHLSN, NQO1 | TDP1 2019/4885ALDH1A1 480/4885MAPK1 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.