Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | GPR132 | Q9UNW8 | 11/20 | 0.56 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.56 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369856 | 0.84 | GPR132 (0.59) | NR4A2CYP19A1PTPN1ALDH1A1LMNA | |
| SCHEMBL2394585 | 0.84 | PLOD2 (0.58) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9366769 | 0.81 | MAOB (0.68) | NR4A2PTPN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL18906070 | 0.81 | MRGPRX4 (0.67) | NR4A2SMN1; SMN2 | |
| SCHEMBL18906065 | 0.81 | NR4A2 (0.71) | NR4A2GPR132CMKLR2CMKLR1 | |
| SCHEMBL2785216 | 0.80 | NR4A2 (0.70) | NR4A2CYP19A1PTPN1ALDH1A1MAOB | |
| Acetic Acid SCHEMBL27351298 | 0.80 | KMT2A (0.58) | ALDH1A1LMNATHRBSMN1; SMN2MAOB | |
| SCHEMBL9366574 | 0.80 | LRRK2 (0.56) | ALDH1A1LMNATHRBSMN1; SMN2MAOB | |
| SCHEMBL30150593 | 0.80 | RAB9A (0.62) | ALDH1A1 | |
| SCHEMBL1323646 | 0.80 | RAB9A (0.62) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391624-B1 | Substituted 1-[3-heteroarylmethoxy)phenyl] alkanols and related compounds in the treatment of asthma, arthritis and related diseases | PFIZER (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5248685-A | Substituted 1-[3-(heteroarylmethoxy)phenyl]alkanols and related compounds in the treatment of asthma | PFIZER INC. (US) | 1993-09-28 | — | — | US | disclosed |
| WO-1990012006-A1 | SUBSTITUTED 1-[3-(HETEROARYLMETHOXY)PHENYL]ALKANOLS AND RELATED COMPOUNDS IN THE TREATMENT OF ASTHMA, ARTHRITIS AND RELATED DISEASES | PFIZER INC. (US) | 1990-10-18 | — | — | WO | disclosed |
| EP-0391624-A1 | Substituted 1-[3-heteroarylmethoxy)phenyl] alkanols and related compounds in the treatment of asthma, arthritis and related diseases | PFIZER INC. (US) | 1990-10-10 | — | — | EP | disclosed |