Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368764 | 0.87 | NLRP3 (0.33) | ALDH1A1HTTNLRP3TDP1KDM4E | |
| SCHEMBL9368867 | 0.86 | HPGD (0.40) | ALDH1A1HTTNLRP3TDP1KDM4E | |
| SCHEMBL9368573 | 0.85 | TDP1 (0.38) | ALDH1A1HTTNLRP3TDP1KDM4E | |
| SCHEMBL9369273 | 0.79 | NLRP3 (0.37) | ALDH1A1HTTNLRP3TDP1KDM4E | |
| SCHEMBL9373264 | 0.77 | NLRP3 (0.37) | ALDH1A1HTTNLRP3TDP1KDM4E | |
| SCHEMBL9371953 | 0.77 | NLRP3 (0.35) | ALDH1A1HTTNLRP3TDP1KDM4E | |
| SCHEMBL9368843 | 0.75 | MEN1 (0.39) | ALDH1A1HTTNLRP3TDP1KDM4E | |
| SCHEMBL9368050 | 0.75 | NLRP3 (0.34) | ALDH1A1HTTNLRP3TDP1KDM4E | |
| SCHEMBL8744754 | 0.75 | NLRP3 (0.34) | ALDH1A1HTTNLRP3KDM4ESMN1; SMN2 | |
| SCHEMBL9368759 | 0.74 | GABRA1 (0.39) | ALDH1A1HTTNLRP3SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377893-B1 | 3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5186737-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5045560-A | Insecticides, nematocides, fungicides, herbicides, human and veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0377893-A2 | 3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1990-07-18 | — | — | EP | disclosed |