Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372436 | 0.82 | NLRP3 (0.43) | TSPOALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL3213534 | 0.82 | ALDH1A1 (0.55) | PIN1TRPM8TSPOALDH1A1TSHR | |
| SCHEMBL5941081 | 0.82 | PIN1 (0.56) | PIN1TRPM8ALDH1A1TSHRMAPK1 | |
| SCHEMBL691909 | 0.81 | SMN1; SMN2 (0.56) | PIN1TRPM8ALDH1A1TSHRMAPK1 | |
| SCHEMBL9686760 | 0.81 | PIN1 (0.53) | PIN1TRPM8ALDH1A1TSHRMAPK1 | |
| SCHEMBL3211799 | 0.80 | PIN1 (0.52) | PIN1TRPM8ALDH1A1TSHRMAPK1 | |
| SCHEMBL3213531 | 0.80 | PIN1 (0.52) | PIN1TRPM8ALDH1A1TSHRMAPK1 | |
| SCHEMBL4433228 | 0.80 | PIN1 (0.52) | PIN1TRPM8ALDH1A1TSHRMAPK1 | |
| SCHEMBL15173708 | 0.79 | PIN1 (0.54) | PIN1TRPM8ALDH1A1TSHRMAPK1 | |
| SCHEMBL15173707 | 0.78 | PIN1 (0.53) | PIN1TRPM8ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377893-B1 | 3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5186737-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5045560-A | Insecticides, nematocides, fungicides, herbicides, human and veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0377893-A2 | 3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1990-07-18 | — | — | EP | disclosed |