Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.53 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368612 | 0.99 | PTGES (0.52) | PTGESALOX5LTC4SNPC1RAB9A | |
| SCHEMBL9369194 | 0.94 | NPC1 (0.49) | PTGESALOX5LTC4SNPC1RAB9A | |
| SCHEMBL9368458 | 0.92 | PTGES (0.45) | PTGESALOX5LTC4SNPC1RAB9A | |
| SCHEMBL9541373 | 0.88 | SLC7A5 (0.52) | PTGESALOX5LTC4SNPC1RAB9A | |
| SCHEMBL9541159 | 0.87 | SLC7A5 (0.50) | PTGESALOX5LTC4SNPC1RAB9A | |
| SCHEMBL9538619 | 0.86 | NR3C1 (0.46) | PTGESALOX5KMT2AMEN1PPARG | |
| SCHEMBL9372894 | 0.86 | PTGES (0.55) | PTGESALOX5LTC4SNPC1RAB9A | |
| SCHEMBL9372874 | 0.86 | PTGES (0.55) | PTGESALOX5LTC4SNPC1NR1H4 | |
| SCHEMBL9369224 | 0.82 | ACACB (0.46) | KMT2A | |
| SCHEMBL1789016 | 0.82 | MAPT (0.51) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |