Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369122 | 0.80 | MME (0.50) | EGLN1MMEACEACE2 | |
| SCHEMBL9365279 | 0.76 | SMN1; SMN2 (0.48) | MMP13LMNAGAAHTT | |
| SCHEMBL11341651 | 0.72 | FDPS (0.56) | SLC6A2GGPS1TSHRMMP8 | |
| SCHEMBL3558478 | 0.70 | SMN1; SMN2 (0.47) | SLC6A2MMEACEMMP8 | |
| SCHEMBL8578336 | 0.70 | MMP8 (0.47) | MMELMNAACEMMP8 | |
| SCHEMBL3558475 | 0.70 | SMN1; SMN2 (0.47) | SLC6A2MMEACEMMP8 | |
| SCHEMBL2659135 | 0.70 | PTPN1 (0.51) | LMNAMMP8 | |
| SCHEMBL17300282 | 0.69 | RIPK1 (0.50) | MMEACEMMP8 | |
| SCHEMBL17300284 | 0.68 | MMP8 (0.44) | MMEACEMMP8 | |
| SCHEMBL7362621 | 0.68 | LMNA (0.39) | MMP13ABCC4LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419327-B1 | Amino acid derivatives, method for their preparation and their therapeutic application | BIOPROJET SOC CIV (FR) | 1994-07-27 | — | — | EP | claimed |