Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 13/20 | 0.50 |
| ▸ | MEP1A | Q16819 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373488 | 0.89 | PTPN1 (0.51) | MEP1BPTPN1ALOX5 | |
| SCHEMBL9538619 | 0.85 | NR3C1 (0.46) | MEP1BMEP1APTPN1ALOX5 | |
| SCHEMBL9372874 | 0.84 | PTGES (0.55) | MEP1BMEP1AALOX5 | |
| SCHEMBL9372894 | 0.84 | PTGES (0.55) | MEP1BMEP1AALOX5 | |
| SCHEMBL765921 | 0.81 | FOLH1 (0.61) | MEP1BFOLH1ANPEPENPEP | |
| SCHEMBL9369252 | 0.81 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9376678 | 0.79 | PTGES (0.47) | MEP1BMEP1AALOX5FOLH1ANPEP | |
| SCHEMBL8792890 | 0.78 | MRGPRX4 (0.52) | ALOX5FOLH1ANPEPENPEP | |
| SCHEMBL6952400 | 0.75 | PTPN1 (0.68) | MEP1BMEP1APTPN1FOLH1 | |
| SCHEMBL9374304 | 0.75 | MRGPRX4 (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |