Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368700 | 0.91 | PTPN1 (0.47) | NR3C1CETPPTPN1ALOX5MAPT | |
| SCHEMBL9368612 | 0.87 | PTGES (0.52) | CETPALOX5SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9538478 | 0.86 | PTGES (0.53) | ALOX5MEN1KMT2APTGESPPARG | |
| SCHEMBL9369316 | 0.85 | MEP1B (0.50) | PTPN1ALOX5MEP1AMEP1B | |
| SCHEMBL1789016 | 0.84 | MAPT (0.51) | SMN1; SMN2MAPTTDP1KMT2AL3MBTL1 | |
| SCHEMBL9368458 | 0.83 | PTGES (0.45) | ALOX5MAPTTDP1MEN1KMT2A | |
| SCHEMBL9369194 | 0.82 | NPC1 (0.49) | CETPALOX5MEN1KMT2APTGES | |
| SCHEMBL9369195 | 0.81 | SLC7A5 (0.44) | ALOX5SMN1; SMN2MAPTTDP1 | |
| SCHEMBL9369770 | 0.81 | MRGPRX4 (0.56) | SMN1; SMN2 | |
| SCHEMBL9369224 | 0.78 | ACACB (0.46) | SMN1; SMN2MAPTTDP1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |