Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537598 | 0.81 | LMNA (0.51) | LMNAKDM4EMEN1ALOX15ALOX12 | |
| SCHEMBL8361113 | 0.81 | LMNA (0.77) | LMNAKDM4EMEN1ALOX15ALOX12 | |
| SCHEMBL9538139 | 0.79 | LMNA (0.49) | LMNAKDM4EMEN1ALOX15ALOX12 | |
| SCHEMBL9537139 | 0.78 | LMNA (0.48) | LMNAKDM4EMEN1ALOX15ALOX12 | |
| SCHEMBL9537873 | 0.78 | S1PR1 (0.43) | LMNAKDM4EMEN1ALOX15ALOX12 | |
| SCHEMBL1354666 | 0.76 | ADORA2A (0.61) | LMNAMEN1KMT2AADORA2AGAA | |
| SCHEMBL31098649 | 0.76 | S1PR3 (0.55) | KDM4ES1PR3GAAS1PR1 | |
| SCHEMBL29289785 | 0.76 | S1PR3 (0.55) | KDM4ES1PR3GAAS1PR1 | |
| SCHEMBL9538546 | 0.76 | LMNA (0.46) | LMNAKDM4EMEN1ALOX15ALOX12 | |
| SCHEMBL8361111 | 0.75 | LMNA (0.68) | LMNAKDM4EMEN1ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278453-B1 | 2,4- and 2,5-Pyridine-dicarboxylic-acid derivatives, process for their preparation, their use and medicines based on these compounds | HOECHST AG (DE) | 1994-12-28 | — | — | EP | claimed |
| EP-0198202-B1 | NOVEL N-CYCLOHEXYL-POLYCARBOXAMIDE COMPOUND AND DERIVATIVES THEREOF, PROCESSES FOR PREPARING THEM, AND USE OF THEM IN PREPARATION OF HOST-GUEST COMPLEXES | MITSUBISHI CORPORATION (JP) | 1991-07-17 | — | — | EP | claimed |
| US-4785111-A | SEPARATION OF COMPOUNDS BY FORMATION OF INCLUSION COMPOUNDS | MITSUBISHI CORPORATION (JP) | 1988-11-15 | — | — | US | claimed |
| EP-0198202-A2 | Novel N-cyclohexyl-polycarboxamide compound and derivatives thereof, processes for preparing them, and use of them in preparation of host-guest complexes | MITSUBISHI CORPORATION (JP) | 1986-10-22 | — | — | EP | claimed |
| EP-0198202-B1 | NOVEL N-CYCLOHEXYL-POLYCARBOXAMIDE COMPOUND AND DERIVATIVES THEREOF, PROCESSES FOR PREPARING THEM, AND USE OF THEM IN PREPARATION OF HOST-GUEST COMPLEXES | MITSUBISHI CORPORATION (JP) | 1991-07-17 | — | — | EP | disclosed |
| US-4785111-A | SEPARATION OF COMPOUNDS BY FORMATION OF INCLUSION COMPOUNDS | MITSUBISHI CORPORATION (JP) | 1988-11-15 | — | — | US | disclosed |
| EP-0198202-A2 | Novel N-cyclohexyl-polycarboxamide compound and derivatives thereof, processes for preparing them, and use of them in preparation of host-guest complexes | MITSUBISHI CORPORATION (JP) | 1986-10-22 | — | — | EP | disclosed |