Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.58 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.58 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19246212 | 0.80 | HPGD (0.74) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL11318957 | 0.78 | CTSD (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4HPGD | |
| SCHEMBL11437411 | 0.77 | ALDH1A1 (0.60) | HPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6819599 | 0.77 | MAPT (0.64) | HPGDALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL8816782 | 0.76 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4PPARG | |
| SCHEMBL16062756 | 0.76 | HPGD (0.60) | HPGDALDH1A1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL16062752 | 0.76 | HPGD (0.60) | HPGDALDH1A1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL7609032 | 0.75 | CHRNB2 (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4PPARG | |
| SCHEMBL8614650 | 0.75 | KMT2A (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4PPARG | |
| SCHEMBL7517695 | 0.74 | NPC1 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291969-B1 | Tetrazole intermediates to antihypertensive compounds | DU PONT (US) | 1994-02-16 | — | — | EP | disclosed |
| US-4874867-A | Tetrazole intermediates to antihypertensive compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| US-4870186-A | Tetrazole intermediates to antihypertensive compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| US-4820843-A | Tetrazole intermediates to antihypertensive compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0291969-A2 | Tetrazole intermediates to antihypertensive compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-23 | — | — | EP | disclosed |