Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 7/20 | 0.36 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | CA9 | Q16790 | 6/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306514 | 0.81 | CDC25C (0.40) | POLB | |
| SCHEMBL13060284 | 0.74 | POLB (0.48) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL12765730 | 0.73 | TSHR (0.67) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL2987144 | 0.71 | APP (0.58) | HIF1ACA12CA2CA9CA1 | |
| SCHEMBL9375607 | 0.69 | KMT2A (0.50) | TSHRKDM4EPOLBMAPK1 | |
| SCHEMBL13973324 | 0.68 | TSHR (0.54) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL22551107 | 0.67 | CA12 (0.56) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL9015439 | 0.67 | LOXL2 (0.40) | TSHRANPEPERAP2ADRB2 | |
| SCHEMBL15726050 | 0.67 | MPO (0.60) | TSHRCYP2D6HIF1APKMKDM4E | |
| SCHEMBL14835275 | 0.67 | TSHR (0.41) | TSHRCYP2D6HIF1ACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417870-B1 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | DIAGNOSTIKFORSCHUNG INST (DE) | 1994-07-20 | — | — | EP | disclosed |
| EP-0417870-A2 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1991-03-20 | — | — | EP | disclosed |