Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307736 | 0.93 | KMT2A (0.48) | KMT2AMEN1LMNAL3MBTL1MAOB | |
| SCHEMBL9306614 | 0.80 | THRB (0.53) | KMT2AMEN1LMNAL3MBTL1KDM4E | |
| SCHEMBL3159042 | 0.71 | LMNA (0.68) | KMT2AMEN1LMNAL3MBTL1MAOB | |
| SCHEMBL10411241 | 0.71 | KMT2A (0.61) | KMT2AMEN1LMNAL3MBTL1MAOB | |
| SCHEMBL7294757 | 0.70 | CYP3A4 (0.52) | KMT2AMEN1LMNAL3MBTL1MAOB | |
| SCHEMBL456924 | 0.69 | L3MBTL1 (0.69) | KMT2AMEN1L3MBTL1MAOBKDM4E | |
| SCHEMBL9015439 | 0.69 | LOXL2 (0.40) | MAOBALDH1A1GFERTSHR | |
| Hydrochloric Acid SCHEMBL6122085 | 0.69 | KMT2A (0.69) | KMT2AMEN1LMNAL3MBTL1MAOB | |
| SCHEMBL9369552 | 0.69 | TSHR (0.38) | KDM4EMAPK1POLBTSHR | |
| Hydrochloric Acid SCHEMBL6298735 | 0.68 | L3MBTL1 (0.67) | KMT2AMEN1L3MBTL1MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417870-B1 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | DIAGNOSTIKFORSCHUNG INST (DE) | 1994-07-20 | — | — | EP | disclosed |
| EP-0417870-A2 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1991-03-20 | — | — | EP | disclosed |