Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369552 | 0.81 | TSHR (0.38) | POLB | |
| SCHEMBL13003576 | 0.77 | ITGA4 (0.47) | CDC25CMEN1KMT2APOLBLMNA | |
| SCHEMBL9306614 | 0.72 | THRB (0.53) | MEN1KMT2APOLBLMNA | |
| SCHEMBL8829958 | 0.71 | LOXL2 (0.50) | MEN1KMT2ALMNACHRM2LOXL2 | |
| SCHEMBL9307566 | 0.70 | POLB (0.55) | MEN1KMT2APOLBGAACCR6 | |
| SCHEMBL12765730 | 0.68 | TSHR (0.67) | LMNA | |
| SCHEMBL2240896 | 0.67 | LOXL2 (0.52) | MEN1KMT2APOLBLMNACHRM2 | |
| SCHEMBL2240772 | 0.67 | TSHR (0.58) | MEN1KMT2APOLBLMNALOXL2 | |
| SCHEMBL4469551 | 0.67 | CHRM2 (0.58) | MEN1KMT2ACHRM2PTPRFPTPN2 | |
| SCHEMBL27522422 | 0.67 | KEAP1 (0.59) | MEN1KMT2APOLBGAAPTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417870-B1 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | DIAGNOSTIKFORSCHUNG INST (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5302370-A | Form complexes with rhenium and technetium | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1994-04-12 | — | — | US | disclosed |
| EP-0417870-A2 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1991-03-20 | — | — | EP | disclosed |