Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775575 | 0.75 | NOS2 (0.33) | — | |
| SCHEMBL9369639 | 0.75 | L3MBTL1 (0.41) | — | |
| SCHEMBL9369801 | 0.73 | FGFR1 (0.35) | NR4A1NR4A2 | |
| SCHEMBL9369497 | 0.69 | CHRNB2 (0.31) | — | |
| SCHEMBL9369105 | 0.69 | RPS6KA5 (0.38) | — | |
| SCHEMBL9371807 | 0.68 | FGFR1 (0.35) | — | |
| SCHEMBL9369020 | 0.68 | ADORA2B (0.33) | — | |
| SCHEMBL369552 | 0.66 | PLK1 (0.31) | — | |
| SCHEMBL9012028 | 0.61 | L3MBTL1 (0.47) | NR4A1NR4A2 | |
| SCHEMBL11459475 | 0.59 | NR4A1 (0.47) | NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244803-B1 | Novel dopamine beta hydroxylase inhibitors | MERRELL DOW PHARMA (US) | 1994-10-26 | — | — | EP | disclosed |
| EP-0244803-A2 | Novel dopamine beta hydroxylase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-11-11 | — | — | EP | disclosed |