Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 8/20 | 0.42 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372896 | 0.89 | ALDH1A1 (0.47) | MAPK7ALDH1A1HPGDCASP1MPI | |
| SCHEMBL9374322 | 0.87 | TNK2 (0.48) | TNK2MAPK7ALDH1A1LRRK2 | |
| SCHEMBL16979656 | 0.78 | BRD4 (0.52) | MAPK7ALDH1A1HPGDCACNA1BAPBA1 | |
| SCHEMBL8546607 | 0.74 | L3MBTL1 (0.42) | MAPK7ALDH1A1HPGDCASP1MPI | |
| SCHEMBL20094162 | 0.73 | MAPK7 (0.51) | MAPK7ALDH1A1HPGDCASP1MPI | |
| SCHEMBL9370046 | 0.71 | BRD4 (0.48) | MAPK7ALDH1A1HPGDCASP1MPI | |
| SCHEMBL10098791 | 0.70 | TNK2 (0.56) | TNK2MAPK7LRRK2 | |
| SCHEMBL19496544 | 0.69 | MAPK7 (0.52) | MAPK7ALDH1A1HPGDCASP1MPI | |
| SCHEMBL9174480 | 0.69 | RAB9A (0.60) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10391266 | 0.69 | RAB9A (0.69) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393530-B1 | 5,11-dihydro-6H-pyrido[2,3,-b][1,4]benzodiazepin-6-ones and -thiones and their use in the prevention or treatment of AIDS | BOEHRINGER INGELHEIM PHARMA (US) | 1994-12-28 | — | — | EP | disclosed |