Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.50 |
| ▸ | MAOA | P21397 | 6/20 | 0.50 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370437 | 0.86 | MAOB (0.50) | MAOBMAOAHMOX1AR | |
| SCHEMBL1932255 | 0.80 | ALOX5 (0.50) | MAOBMAOA | |
| Hydrochloric Acid SCHEMBL18686893 | 0.79 | MEN1 (0.51) | MAOBMAOA | |
| SCHEMBL11426612 | 0.78 | MAOB (0.67) | MAOBHMOX1IDO1 | |
| SCHEMBL508476 | 0.77 | MAOB (0.70) | MAOBMAOAHMOX1IDO1 | |
| SCHEMBL5511955 | 0.77 | MAOB (0.70) | MAOBMAOAHMOX1IDO1 | |
| SCHEMBL5512565 | 0.77 | MAOB (0.59) | MAOBMAOA | |
| SCHEMBL1843485 | 0.74 | NOS3 (0.52) | — | |
| SCHEMBL29442849 | 0.74 | NOS3 (0.52) | — | |
| Hydrochloric Acid SCHEMBL19584238 | 0.73 | NOS3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321385-B1 | Substituted thienoimidazole derivatives, process for their preparation, pharmaceutical compositions containing them and their use as gastric secretion inhibitors | HOECHST AG (DE) | 1994-08-17 | — | — | EP | disclosed |
| US-5114955-A | Derivatives with pyridine as gastrointestinal disorders and antisecretory agents | HOECHST AKETIENGESELLSCHAFT (DE) | 1992-05-19 | — | — | US | disclosed |
| EP-0321385-A2 | Substituted thienoimidazole derivatives, process for their preparation, pharmaceutical compositions containing them and their use as gastric secretion inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-06-21 | — | — | EP | disclosed |