SCHEMBL9370337

SCHEMBL9370337

CNS(=O)(=O)c1scc(C)c1C

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 2/20 0.36
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
HTT P42858 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9424470 0.76 CA2 (0.34) CA12CA1CA2CA3CA6
SCHEMBL15147318 0.67 GAA (0.31) SMN1; SMN2GAA
SCHEMBL3923958 0.67 LMNA (0.40) SMN1; SMN2GAALMNACA12CA1
SCHEMBL31664536 0.65 KDM4E (0.38) SMN1; SMN2GAALMNACA12CA1
SCHEMBL27685148 0.64 L3MBTL1 (0.44) GAALMNAALDH1A1
SCHEMBL14271757 0.64 ACHE (0.33) GAALMNACA1CA2HTT
SCHEMBL9386310 0.61 PFKFB3 (0.48) ALDH1A1
SCHEMBL24269966 0.60 LMNA (0.46) SMN1; SMN2GAALMNACA1CA2
SCHEMBL22021504 0.60 EDNRB (0.39) SMN1; SMN2GAALMNACA12CA1
SCHEMBL25735693 0.60 CA12 (0.38) SMN1; SMN2GAALMNACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281110-B1 N-[2-(pyridyl)propyl]-N-substituted sulfonamide, herbicide containing the same as an active ingredient and intermediate thereof MITSUBISHI CHEM IND (JP) 1994-09-07 EP disclosed
US-4960897-A Herbicide containing 1-(halogenomethyl)-vinyl pyridines MITSUBISHI KASEI CORPORATION (JP) 1990-10-02 US disclosed
EP-0281110-A2 N-[2-(pyridyl)propyl]-N-substituted sulfonamide, herbicide containing the same as an active ingredient and intermediate thereof MITSUBISHI KASEI CORPORATION (JP) 1988-09-07 EP disclosed