Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.73 |
| ▸ | KIF11 | P52732 | 5/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18255056 | 0.84 | RIPK1 (1.00) | LMNARIPK1KIF11GAA | |
| SCHEMBL18248229 | 0.84 | TERT (0.72) | LMNARIPK1GAAMAOB | |
| SCHEMBL1658926 | 0.81 | NT5E (0.82) | KIF11EGFRNT5EACHEMAOB | |
| SCHEMBL14540797 | 0.80 | PDE5A (0.60) | RIPK1KIF11EGFRNT5EGAA | |
| SCHEMBL18248225 | 0.80 | RIPK1 (0.63) | LMNARIPK1GAAMAOB | |
| SCHEMBL23269369 | 0.79 | BCL2 (0.64) | RIPK1MAOB | |
| SCHEMBL18248378 | 0.79 | TERT (0.76) | LMNARIPK1GAA | |
| SCHEMBL18248291 | 0.78 | TERT (0.68) | LMNARIPK1ACHEMAOB | |
| SCHEMBL28473652 | 0.77 | MAOB (0.79) | KIF11EGFRNT5EACHEMAOB | |
| SCHEMBL9676881 | 0.77 | RIPK1 (0.59) | LMNARIPK1KIF11GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322691-B1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS (JP) | 1994-06-15 | — | — | EP | claimed |
| US-4895947-A | Process for producing 1-acyl-2-pyrazoline derivative | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-01-23 | — | — | US | claimed |
| EP-0322691-A1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | claimed |
| EP-0322691-B1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS (JP) | 1994-06-15 | — | — | EP | disclosed |
| CN-1015177-B | Method for producing 1-acyl-2-pyrazoline derivative | MITSUI TOATSU CHEMICALS (JP) | 1991-12-25 | — | — | CN | disclosed |
| US-4895947-A | Process for producing 1-acyl-2-pyrazoline derivative | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-01-23 | — | — | US | disclosed |
| CN-1033994-A | Produce the method for 1-acyl-2-pyrazoline derivative | MITSUI TOATSU CHEMICALS (JP) | 1989-07-19 | — | — | CN | disclosed |
| EP-0322691-A1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | disclosed |