Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23856959 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL9464622 | 0.76 | MAPT (0.57) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL30334623 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL9370934 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL29203096 | 0.75 | ALDH1A1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL6382115 | 0.73 | ACHE (0.54) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL9373350 | 0.72 | L3MBTL1 (0.33) | ALDH1A1KMT2ALMNAMAOACYP1A2 | |
| SCHEMBL23857269 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL30047239 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL29203109 | 0.70 | KDM4E (0.57) | ALDH1A1MAPTKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425946-B1 | Iso- and heterocyclic phenylsulphonamides | BAYER AG (DE) | 1994-08-17 | — | — | EP | disclosed |
| US-5264458-A | Antithrombotic iso- and heterocyclic phenylsulphonamides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-23 | — | — | US | disclosed |
| US-5191092-A | ANTITHROMBOTIC ISO- AND HETEROCYCLIC PHENYLSULPHONAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0425946-A2 | Iso- and heterocyclic phenylsulphonamides | BAYER AG (DE) | 1991-05-08 | — | — | EP | disclosed |