Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.48 |
| ▸ | CPT1A | P50416 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 3/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.37 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17558298 | 0.84 | DGAT2 (0.45) | CPT2CPT1ACHRM2DGAT2MGAT2 | |
| SCHEMBL2595265 | 0.82 | CHRM2 (0.40) | CPT2CPT1ACHRM2FABP4FABP5 | |
| SCHEMBL9370592 | 0.76 | CHRM2 (0.46) | CPT2CPT1ACHRM2DGAT2MGAT2 | |
| SCHEMBL8871811 | 0.76 | CHRM2 (0.55) | CHRM2EPHX2 | |
| SCHEMBL2596230 | 0.75 | SLC6A2 (0.44) | CPT2CPT1ASLC6A2SLC6A4CHRM2 | |
| SCHEMBL2584012 | 0.74 | EPHX2 (0.42) | CHRM2EPHX2OPRM1OPRK1 | |
| SCHEMBL2584008 | 0.74 | EPHX2 (0.42) | CHRM2EPHX2OPRM1OPRK1 | |
| SCHEMBL2593264 | 0.72 | SLC6A2 (0.41) | CPT2CPT1ASLC6A2SLC6A4CHRM2 | |
| SCHEMBL2596235 | 0.71 | SLC6A2 (0.46) | CPT2CPT1ASLC6A2SLC6A4CHRM2 | |
| SCHEMBL18983754 | 0.69 | CHRM2 (0.43) | CHRM2DGAT2MGAT2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569319-A1 | HETEROARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011141396-A1 | HETEROARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-11-17 | — | — | WO | disclosed |