Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.40 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367766 | 0.94 | NAMPT (0.46) | CHRM2HRH4HRH3TBXAS1TERT | |
| SCHEMBL8466104 | 0.83 | CHRM2 (0.53) | CHRM2HRH4HRH3TERTSIGMAR1 | |
| SCHEMBL9021157 | 0.81 | SIGMAR1 (0.63) | TBXAS1SIGMAR1TAAR1 | |
| SCHEMBL9368553 | 0.81 | NAMPT (0.45) | TBXAS1TERTSIGMAR1NAMPTL3MBTL1 | |
| SCHEMBL27220846 | 0.77 | TERT (0.56) | TBXAS1TERTNAMPTTAAR1 | |
| SCHEMBL9020813 | 0.76 | DRD2 (0.52) | TBXAS1TERTNAMPTTAAR1 | |
| SCHEMBL29109594 | 0.75 | TERT (0.51) | HRH4HRH3TBXAS1TERTSIGMAR1 | |
| SCHEMBL9367781 | 0.74 | TAAR1 (0.49) | TBXAS1SIGMAR1NAMPTTSHRTAAR1 | |
| SCHEMBL28712307 | 0.74 | TBXAS1 (0.46) | HRH4HRH3TBXAS1TERTSIGMAR1 | |
| SCHEMBL28717110 | 0.74 | TBXAS1 (0.46) | HRH4HRH3TBXAS1TERTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |