Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | F2 | P00734 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367753 | 0.90 | LTA4H (0.71) | LTA4HRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL9367030 | 0.86 | MEN1 (0.74) | LTA4HRAB9ASMN1; SMN2NPC1HPGD | |
| Benzene SCHEMBL11566961 | 0.86 | EPHX2 (0.76) | RAB9ASMN1; SMN2NPC1LMNAALDH1A1 | |
| SCHEMBL2205445 | 0.86 | EPHX2 (0.76) | RAB9ASMN1; SMN2NPC1LMNAALDH1A1 | |
| SCHEMBL9366598 | 0.85 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1HPGDLMNA | |
| SCHEMBL7322517 | 0.83 | RAB9A (0.77) | RAB9ASMN1; SMN2NPC1LMNAALDH1A1 | |
| SCHEMBL13528798 | 0.82 | EPHX2 (0.61) | RAB9ASMN1; SMN2NPC1HPGDLMNA | |
| SCHEMBL9366570 | 0.81 | RAB9A (0.64) | LTA4HRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL8331684 | 0.80 | MEN1 (0.79) | RAB9ASMN1; SMN2NPC1LMNAMEN1 | |
| SCHEMBL2184045 | 0.80 | WNT3A (0.80) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409163-B1 | Novel cyclic vinylogous N-hydroxy-N-methylureas useful as 5-lipoxygenase inhibitors | MERRELL DOW PHARMA (US) | 1994-12-21 | — | — | EP | disclosed |