Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL22557988 | 1.00 | LMNA (0.53) | LMNAALOX15BLMPMP22ACHE | |
| Trifluoroacetic Acid SCHEMBL29921600 | 1.00 | LMNA (0.53) | LMNAALOX15BLMPMP22ACHE | |
| Trifluoroacetic Acid SCHEMBL5744812 | 1.00 | LMNA (0.53) | LMNAALOX15BLMPMP22ACHE | |
| Trifluoroacetic Acid SCHEMBL6542389 | 0.88 | LMNA (0.39) | LMNAALOX15BLMPMP22ACHE | |
| Trifluoroacetic Acid SCHEMBL3945276 | 0.87 | FFAR3 (0.47) | LMNAALOX15BLMPMP22FFAR3 | |
| Trifluoroacetic Acid SCHEMBL5747984 | 0.86 | ALDH1A1 (0.46) | LMNAALOX15BLMPMP22ACHE | |
| Trifluoroacetic Acid SCHEMBL3906649 | 0.86 | ALDH1A1 (0.46) | LMNAALOX15BLMPMP22ACHE | |
| Trifluoroacetic Acid SCHEMBL934980 | 0.86 | ACHE (0.54) | LMNAALOX15BLMPMP22ACHE | |
| Trifluoroacetic Acid SCHEMBL15533970 | 0.86 | ACHE (0.54) | LMNAALOX15BLMPMP22ACHE | |
| Trifluoroacetic Acid SCHEMBL479935 | 0.86 | FFAR3 (0.54) | LMNAALOX15BLMPMP22FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026094-A | Substituted 4-azaindoles and their use as modulators of the G L UN2B receptor | 詹森药业有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-104271552-B | Substituted heterocyclic acetamides as KAPPA Opioid Receptor (KOR) agonists | 雷迪博士实验室有限公司 | 2017-08-08 | — | — | CN | claimed |
| CN-103189373-A | Substituted triazolopyridines | BAYER IP GMBH | 2013-07-03 | — | — | CN | claimed |
| WO-2010147234-A1 | DIARYLAMIDE-SPIRODIAMINE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-12-23 | — | — | WO | claimed |
| CN-1759118-B | Diazepinoindole derivatives as kinase inhibitors | PFIZER | 2010-12-08 | — | — | CN | claimed |
| EP-2249646-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | Glaxo Group Limited (GB) | 2010-11-17 | — | — | EP | claimed |
| CN-101107249-B | purine derivatives as A2A receptor agonists | NOVARTIS AG | 2010-10-13 | — | — | CN | claimed |
| CN-101511429-A | Indulines derivatives and gpr119 agonists | SMITHKLINE BEECHAM CORP (US) | 2009-08-19 | — | — | CN | claimed |
| WO-2009100169-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | claimed |
| CN-101360716-A | Novel 2-amino-imidazole-4-one compounds and their use in the manufacture of a medicament to be used in the treatment of cognitive impairment, alzheimer s disease, neurodegeneration and dementia | ASTRAZENECA AB (SE) | 2009-02-04 | — | — | CN | claimed |
| EP-1699791-A1 | NOVEL TRICYCLIC SPIRODERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2006-09-13 | — | — | EP | claimed |
| CN-1759118-A | Diazepinoindole derivatives as kinase inhibitors | PFIZER (US) | 2006-04-12 | — | — | CN | claimed |
| CN-1229343-C | Novel compounds | ASTRAZENECA AB (SE) | 2005-11-30 | — | — | CN | claimed |
| WO-2005105814-A1 | TETRACYCLIC INHIBITORS OF JANUS KINASES | INCYTE CORPORATION (US) | 2005-11-10 | — | — | WO | claimed |
| CN-1675218-A | Novel tricyclic spiropiperidines or spiropyrrolidines | ASTRAZENECA AB (SE) | 2005-09-28 | — | — | CN | claimed |
| WO-2005061499-A1 | NOVEL TRICYCLIC SPIRODERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2005-07-07 | — | — | WO | claimed |
| WO-2005048916-A2 | TETRAHYDROSPIRO-BETA-CARBOLINE-1,3 '-PYRROLIDINE DERIVATIVES AND THEIR USE IN GHSR-RELATED DISORDERS | BIOVITRUM AB (SE) | 2005-06-02 | — | — | WO | claimed |
| CN-1509281-A | Benzimidazol derivatives modulate che mokine receptors | — | 2004-06-30 | — | — | CN | claimed |
| CN-1426393-A | Novel compounds | ASTRAZENECA AB (SE) | 2003-06-25 | — | — | CN | claimed |
| CN-1190395-A | Substituted (sulfonic, sulfinic, sulfonamido or sulfonamido) N- [ aminoiminomethyl) phenylalkyl ] -azaheterocyclic amide compounds | RHONE POULENC RORER PHARMA (US) | 1998-08-12 | — | — | CN | claimed |