Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6542389

CC(=N)N.O=C(O)C(F)(F)F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
ALDH1A1 P00352 2/20 0.33
ACHE P22303 1/20 0.33
TSHR P16473 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
KLK1 P06870 2/20 0.32
KLK5 Q9Y337 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
F2 P00734 2/20 0.32
F11 P03951 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL29019096 0.90 TP53 (0.33) LMNAALOX15BLMPMP22NOS1
Trifluoroacetic Acid SCHEMBL27509737 0.90 LMNA (0.32) LMNAALOX15BLMPMP22NOS1
Trifluoroacetic Acid SCHEMBL7764428 0.88 ACHE (0.38) LMNANOS1NOS2ALDH1A1ACHE
Trifluoroacetic Acid SCHEMBL2409655 0.88 ACHE (0.38) LMNANOS1NOS2ALDH1A1ACHE
Trifluoroacetic Acid SCHEMBL31438646 0.88 ACHE (0.38) LMNANOS1NOS2ALDH1A1ACHE
Trifluoroacetic Acid SCHEMBL5744812 0.88 LMNA (0.53) LMNAALOX15BLMPMP22NOS1
Trifluoroacetic Acid SCHEMBL7442074 0.88 FFAR3 (0.38) LMNAALDH1A1TSHRFFAR3LCK
Trifluoroacetic Acid SCHEMBL937102 0.88 LMNA (0.53) LMNAALOX15BLMPMP22NOS1
Trifluoroacetic Acid SCHEMBL22557988 0.88 LMNA (0.53) LMNAALOX15BLMPMP22NOS1
Trifluoroacetic Acid SCHEMBL29921600 0.88 LMNA (0.53) LMNAALOX15BLMPMP22NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115915795-A Perovskite solar cell containing double-layer trifluoroacetate modification layer and preparation method thereof 河北工业大学 2023-04-04 CN claimed
CN-115915795-A Perovskite solar cell containing double-layer trifluoroacetate modification layer and preparation method thereof 河北工业大学 2023-04-04 CN disclosed
CN-115915795-A Perovskite solar cell containing double-layer trifluoroacetate modification layer and preparation method thereof 河北工业大学 2023-04-04 CN disclosed
EP-1487813-A1 BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES USEFUL IN THE TREATMENT OF HYPER-PROLIFERATIVE DISORDERS Bayer Pharmaceuticals Corporation (US) 2004-12-22 EP disclosed
EP-1282413-A4 HALOGENATED 2-AMINO-5,6 HEPTENOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS PHARMACIA CORP (US) 2004-12-01 EP disclosed
WO-2003072561-A1 BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES USEFUL IN THE TREATMENT OF HYPER-PROLIFERATIVE DISORDERS BAYER PHARMACEUTICALS CORPORATION (US) 2003-09-04 WO disclosed
EP-1282413-A1 HALOGENATED 2-AMINO-5,6 HEPTENOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS Pharmacia Corporation (US) 2003-02-12 EP disclosed
US-6465686-B2 ADMINISTERING HALOGENATED AMIDINO OR OXYAMIDINO COMPOUND TO TREAT DISEASES CAUSED BY NITRIC OXIDE SYNTHASE PHARMACIA CORPORATION 2002-10-15 US disclosed
US-20020049202-A1 Halogenated 2-amino-5,6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors GRAPPERHAUS MARGARET L (US) 2002-04-25 US disclosed
WO-2001078719-A1 HALOGENTATED 2-AMINO-5,6 HEPTENOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS PHARMACIA CORPORATION (US) 2001-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020049202-A1 Halogenated 2-amino-5,6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors ALOX5, PTGIS, ALAD LMNA 4478/4885ALOX15 5/4885BLM 4293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.