Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | KLK1 | P06870 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372436 | 0.84 | NLRP3 (0.43) | NLRP3SMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL9369583 | 0.80 | NLRP3 (0.40) | F2NLRP3SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9374168 | 0.80 | NLRP3 (0.40) | NLRP3SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL9368524 | 0.79 | NLRP3 (0.37) | F2NLRP3SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9376548 | 0.78 | NLRP3 (0.39) | NLRP3SMN1; SMN2CRHR1ALDH1A1KDM4E | |
| SCHEMBL9373260 | 0.76 | ITGB1 (0.39) | NLRP3SMN1; SMN2CRHR1ALDH1A1 | |
| SCHEMBL9368665 | 0.76 | PIN1 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2ATRPM8 | |
| SCHEMBL10366624 | 0.76 | MGAM (0.47) | F2KLK1PRSS1SMN1; SMN2MAPT | |
| SCHEMBL2167246 | 0.76 | NLRP3 (0.51) | NLRP3SMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL9368775 | 0.75 | NLRP3 (0.40) | NLRP3SMN1; SMN2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377893-B1 | 3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5186737-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5045560-A | Insecticides, nematocides, fungicides, herbicides, human and veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0377893-A2 | 3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1990-07-18 | — | — | EP | disclosed |