Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665346 | 0.78 | KDM4E (0.48) | KDM4ETYMPALDH1A1IDH1ALKBH3 | |
| SCHEMBL28313729 | 0.77 | CALM1 (0.58) | CALM1POLBATMKDM4EMAPT | |
| SCHEMBL23718486 | 0.76 | NR3C1 (0.37) | RAB9APOLBATMKDM4EMAPT | |
| SCHEMBL9190942 | 0.75 | CALM1 (0.55) | CALM1POLBATMKDM4EMAPT | |
| SCHEMBL6920607 | 0.75 | MAPT (0.61) | POLBKDM4EMAPTNPSR1GAA | |
| SCHEMBL20828256 | 0.73 | TYMP (0.65) | KDM4ETYMPALDH1A1DAO | |
| SCHEMBL10692060 | 0.72 | KAT8 (0.46) | RAB9AKDM4ETYMPMAPTSTAT1 | |
| SCHEMBL9454876 | 0.72 | PTGS2 (0.44) | KDM4ETYMPMAPTGAAALDH1A1 | |
| SCHEMBL5663531 | 0.72 | TNKS2 (0.49) | POLBKDM4ETYMPALDH1A1IDH1 | |
| SCHEMBL2820256 | 0.71 | CALM1 (0.73) | CALM1KDM4ETYMPMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609328-A1 | PYRROLO-PYRIDAZINES WITH GASTRO-INTESTINAL PROTECTIVE ACTION | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-08-10 | — | — | EP | disclosed |