Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091279 | 0.89 | SIGMAR1 (0.50) | SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL9373860 | 0.85 | SIGMAR1 (0.52) | SIGMAR1MEN1KMT2A | |
| SCHEMBL8096618 | 0.81 | SIGMAR1 (0.53) | SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL1677375 | 0.75 | MTOR (0.65) | SIGMAR1KCNH2CNR1MEN1KMT2A | |
| SCHEMBL9150904 | 0.75 | SIGMAR1 (0.49) | SIGMAR1KCNH2 | |
| SCHEMBL15130899 | 0.73 | SIGMAR1 (0.64) | SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL7022052 | 0.73 | SIGMAR1 (0.64) | SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL8977015 | 0.72 | CYP1A2 (0.46) | SIGMAR1 | |
| SCHEMBL9158629 | 0.72 | ALDH1A1 (0.48) | — | |
| SCHEMBL8976770 | 0.71 | SIGMAR1 (0.43) | SIGMAR1KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591426-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1994-04-13 | — | — | EP | claimed |
| WO-1993000313-A2 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1993-01-07 | — | — | WO | claimed |