Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869697 | 0.90 | CYP1A2 (0.42) | GAACYP1A2MAPTLMNAALDH1A1 | |
| Famoxadone SCHEMBL673443 | 0.84 | MMP2 (0.42) | SIRT1GFERCYP1A2MAPTLMNA | |
| Famoxadone SCHEMBL14128616 | 0.84 | MMP2 (0.42) | SIRT1GFERCYP1A2MAPTLMNA | |
| Famoxadone SCHEMBL63351 | 0.84 | MMP2 (0.42) | SIRT1GFERCYP1A2MAPTLMNA | |
| Famoxadone SCHEMBL17293878 | 0.83 | MMP2 (0.41) | SIRT1GFERCYP1A2MAPTLMNA | |
| SCHEMBL9545815 | 0.79 | MAOB (0.42) | SIRT1ALDH1A1KMT2AMEN1MAOB | |
| SCHEMBL9375723 | 0.78 | PREP (0.36) | SIRT1GAACYP1A2MAPTALDH1A1 | |
| SCHEMBL9207805 | 0.78 | RAB9A (0.40) | SIRT1KMT2AMEN1MAOAMAOB | |
| SCHEMBL9207801 | 0.78 | FFAR1 (0.37) | KMT2AMEN1 | |
| SCHEMBL9370594 | 0.77 | PGR (0.39) | SIRT1LMNAKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630370-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018016-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-16 | — | — | WO | disclosed |