Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Famoxadone SCHEMBL63351 | 0.83 | MMP2 (0.42) | MAPTCYP1A2MEN1KMT2AALDH1A1 | |
| Famoxadone SCHEMBL14128616 | 0.83 | MMP2 (0.42) | MAPTCYP1A2MEN1KMT2AALDH1A1 | |
| Famoxadone SCHEMBL673443 | 0.83 | MMP2 (0.42) | MAPTCYP1A2MEN1KMT2AALDH1A1 | |
| Famoxadone SCHEMBL17293878 | 0.82 | MMP2 (0.41) | MAPTCYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL9869697 | 0.82 | CYP1A2 (0.42) | MAPTCYP1A2HSP90AA1KMT2AALDH1A1 | |
| Famoxadone SCHEMBL28139781 | 0.79 | MMP1 (0.40) | MEN1KMT2AHPGDSIRT1 | |
| Famoxadone SCHEMBL27502240 | 0.79 | MMP2 (0.38) | MAPTCYP1A2HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL9375008 | 0.78 | SIRT1 (0.40) | MAPTCYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL9207805 | 0.78 | RAB9A (0.40) | CA12CA1CA9MEN1KMT2A | |
| SCHEMBL9207801 | 0.78 | FFAR1 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630370-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018016-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-16 | — | — | WO | disclosed |