Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CLTC | Q00610 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | APP | P05067 | 5/20 | 0.45 |
| ▸ | SNCA | P37840 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768442 | 0.84 | MGLL (0.54) | ALDH1A1MAPK1KDM4EMEN1KMT2A | |
| SCHEMBL4693182 | 0.83 | NR1H2 (0.48) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| SCHEMBL28635748 | 0.79 | MAPT (0.52) | ALDH1A1MAPK1TSHRKDM4EMEN1 | |
| SCHEMBL7558814 | 0.78 | CES2 (0.53) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL8331785 | 0.74 | CMA1 (0.70) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| SCHEMBL5049894 | 0.74 | ELANE (0.64) | ALDH1A1MAPK1KDM4EMEN1KMT2A | |
| SCHEMBL7558451 | 0.73 | CA12 (0.48) | ALDH1A1MAPK1KDM4EMEN1KMT2A | |
| SCHEMBL31662937 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MAPK1TSHRCYP3A4TDP1 | |
| SCHEMBL8404372 | 0.70 | CHRM5 (0.56) | ALDH1A1KDM4E | |
| SCHEMBL11360961 | 0.68 | ALDH1A1 (0.81) | ALDH1A1MAPK1TSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630241-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018765-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |