SCHEMBL7558451

SCHEMBL7558451

Cc1ccc(CN2C(=O)C(Cl)=C(Cl)C2=O)cc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA9 Q16790 3/20 0.48
APAF1 O14727 1/20 0.44
CCR2 P41597 1/20 0.43
MAPT P10636 5/20 0.42
TP53 P04637 2/20 0.42
NPBWR1 P48145 1/20 0.42
MAPK1 P28482 4/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 2/20 0.40
HTT P42858 2/20 0.40
ALDH1A1 P00352 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
KMT2A Q03164 1/20 0.40
MCL1 Q07820 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11768442 0.82 MGLL (0.54) CA12CA1CA2CA9MAPT
SCHEMBL28635748 0.81 MAPT (0.52) CA12CA1CA2CA9MAPT
SCHEMBL9757294 0.81 MAPT (0.58) CA12CA1CA2CA9MAPT
SCHEMBL12704614 0.77 APAF1 (0.50) CA12CA1CA2CA9APAF1
SCHEMBL12704612 0.77 APAF1 (0.50) CA12CA1CA2CA9APAF1
SCHEMBL7558814 0.77 CES2 (0.53) CA12CA1CA2CA9APAF1
SCHEMBL10928006 0.73 ALOX15 (0.56) CA12CA1CA2CA9APAF1
SCHEMBL8331785 0.73 CMA1 (0.70) APAF1MAPTMAPK1KDM4EALDH1A1
SCHEMBL9375462 0.73 ALDH1A1 (0.47) MAPTTP53MAPK1KDM4EHPGD
SCHEMBL5049894 0.72 ELANE (0.64) MAPTTP53MAPK1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108415221-B Photosensitive resin composition and application thereof 奇美实业股份有限公司 2023-07-28 CN disclosed
CN-106444285-B Photosensitive resin composition for color filter and application thereof 奇美实业股份有限公司 2021-09-10 CN disclosed
EP-1227111-A1 TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF Yoshitomi Fine Chemicals, Ltd. (JP) 2002-07-31 EP disclosed
EP-0877061-A1 TRIPHENYLBORANE-ROSIN AMINE ADDUCT AND USE OF THE SAME Yoshitomi Fine Chemicals, Ltd. (JP) 1998-11-11 EP disclosed