Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372070 | 0.85 | BACE1 (0.33) | — | |
| SCHEMBL9372258 | 0.82 | ABCC9 (0.34) | — | |
| SCHEMBL9375452 | 0.81 | CHRM1 (0.36) | CHRM1 | |
| SCHEMBL9371993 | 0.74 | MAPT (0.38) | — | |
| SCHEMBL10435504 | 0.72 | KDM4E (0.36) | — | |
| SCHEMBL9372466 | 0.71 | HSD11B1 (0.33) | — | |
| SCHEMBL9372171 | 0.71 | F10 (0.35) | CHRM1 | |
| SCHEMBL10435505 | 0.71 | — | — | |
| SCHEMBL9376272 | 0.71 | ADK (0.32) | — | |
| SCHEMBL9373865 | 0.69 | F10 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371312-B1 | Benzoxazine derivatives | MERCK PATENT GMBH (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5036068-A | Cardiovascular disorders | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-07-30 | — | — | US | disclosed |
| EP-0371312-A1 | Benzoxazine derivatives | MERCK PATENT GmbH (DE) | 1990-06-06 | — | — | EP | disclosed |