Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 5/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372070 | 0.85 | BACE1 (0.33) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL9373191 | 0.84 | BACE1 (0.34) | BACE1KDM4E | |
| SCHEMBL9374693 | 0.72 | ABCC9 (0.33) | BACE1 | |
| SCHEMBL8085076 | 0.71 | NPSR1 (0.34) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL10435504 | 0.71 | KDM4E (0.36) | ADKHTTKDM4ECYP19A1 | |
| SCHEMBL9376016 | 0.71 | HRH4 (0.34) | MEN1HTTRAB9AKMT2ANPSR1 | |
| SCHEMBL9372171 | 0.71 | F10 (0.35) | MAPTMEN1HTTKMT2ABACE1 | |
| SCHEMBL9372466 | 0.71 | HSD11B1 (0.33) | ADKMAPTBACE1GSK3BKDM4E | |
| SCHEMBL9375552 | 0.71 | CHRM1 (0.30) | — | |
| SCHEMBL10435505 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371312-B1 | Benzoxazine derivatives | MERCK PATENT GMBH (DE) | 1994-07-20 | — | — | EP | claimed |