Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452911 | 0.78 | GABRA5 (0.47) | BRPF1GABRA5GABRG2GABRB3IDO1 | |
| SCHEMBL2731241 | 0.73 | BRPF1 (0.44) | BRPF1HSD17B3SIRT6BRD4PTPN1 | |
| SCHEMBL30963678 | 0.73 | BRPF1 (0.44) | BRPF1HSD17B3SIRT6BRD4PTPN1 | |
| SCHEMBL20677715 | 0.69 | GABRA5 (0.59) | GABRA5GABRG2GABRB3TDO2MEN1 | |
| SCHEMBL29821241 | 0.69 | BRPF1 (0.41) | BRPF1HSD17B3SIRT6BRD4MEN1 | |
| SCHEMBL11570160 | 0.69 | TDO2 (0.35) | GABRA5GABRG2GABRB3SIRT6TDO2 | |
| SCHEMBL9391482 | 0.69 | BRPF1 (0.41) | BRPF1HSD17B3SIRT6BRD4MEN1 | |
| SCHEMBL87771 | 0.68 | GABRG2 (0.40) | GABRA5GABRG2GABRB3 | |
| SCHEMBL14511561 | 0.67 | BRPF1 (0.42) | BRPF1HSD17B3SIRT6BRD4PTPN1 | |
| SCHEMBL3959344 | 0.66 | GABRG2 (0.44) | GABRA5GABRG2GABRB3HSD17B3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070098631-A2 | DIAGNOSTIC COMPOUNDS COMPRISING A SCAFFOLD COUPLED TO A SIGNAL ENTITY FOR MEDICAL IMAGING DIAGNOSTIC | GUERBET (FR) | 2007-05-03 | — | — | US | disclosed |
| US-20070098631-A2 | DIAGNOSTIC COMPOUNDS COMPRISING A SCAFFOLD COUPLED TO A SIGNAL ENTITY FOR MEDICAL IMAGING DIAGNOSTIC | GUERBET (FR) | 2007-05-03 | — | — | US | disclosed |
| EP-0590022-A1 | IMIDAZO 1,5-a]QUINOXALINES | PHARMACIA & UPJOHN COMPANY (US) | 1994-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070098631-A2 | DIAGNOSTIC COMPOUNDS COMPRISING A SCAFFOLD COUPLED TO A SIGNAL ENTITY FOR MEDICAL IMAGING DIAGNOSTIC | HTR3D, BRD4, CNR1 | BRPF1 2273/4885GABRA5 64/4885GABRG2 564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.