Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 11/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378613 | 0.89 | ABCC9 (0.33) | ABCC9DRD2DRD3EGLN2BACE1 | |
| SCHEMBL9372276 | 0.86 | ABCC9 (0.34) | ABCC9DRD2DRD3EGLN2DYRK1A | |
| SCHEMBL9371959 | 0.85 | EGLN2 (0.39) | ABCC9DRD2DRD3EGLN2AR | |
| SCHEMBL9372600 | 0.85 | ABCC9 (0.39) | ABCC9 | |
| SCHEMBL9377305 | 0.83 | ABCC9 (0.38) | ABCC9BACE1 | |
| SCHEMBL8088696 | 0.83 | PDE4A (0.37) | ABCC9DRD2DRD3EGLN2KDM4E | |
| SCHEMBL9376786 | 0.82 | DRD2 (0.37) | ABCC9DRD2DRD3EGLN2DYRK1A | |
| SCHEMBL8084526 | 0.82 | ABCC9 (0.36) | ABCC9DRD2DRD3EGLN2KDM4E | |
| SCHEMBL9372773 | 0.81 | DRD2 (0.41) | ABCC9DRD2DRD3EGLN2BACE1 | |
| SCHEMBL9372978 | 0.80 | VCAM1 (0.38) | ABCC9AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371312-B1 | Benzoxazine derivatives | MERCK PATENT GMBH (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5036068-A | Cardiovascular disorders | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-07-30 | — | — | US | disclosed |
| EP-0371312-A1 | Benzoxazine derivatives | MERCK PATENT GmbH (DE) | 1990-06-06 | — | — | EP | disclosed |