Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888608 | 0.80 | CHRNA7 (0.46) | ALDH1A1SMN1; SMN2MAPTHPGDKDM4E | |
| SCHEMBL10013754 | 0.78 | MAOA (0.49) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL3438230 | 0.77 | ALDH1A1 (0.58) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL9377614 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL21370549 | 0.76 | CYP1A1 (0.52) | SMN1; SMN2LMNAMAPTKDM4EKMT2A | |
| SCHEMBL3868257 | 0.74 | ACHE (0.44) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL7926901 | 0.73 | ALDH1A1 (0.45) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL342467 | 0.72 | NQO1 (0.64) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL13243761 | 0.72 | NR1H2 (0.39) | — | |
| SCHEMBL6859076 | 0.72 | MAPT (0.37) | ALDH1A1CYP2A6LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605524-A1 | ANTIBACTERIAL, ANTIMYCOPLASMAL COMPOUNDS RELATED TO MUPIROCIN | SMITHKLINE BEECHAM PLC (GB) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993006118-A1 | ANTIBACTERIAL, ANTIMYCOPLASMAL COMPOUNDS RELATED TO MUPIROCIN | SMITHKLINE BEECHAM PLC (GB) | 1993-04-01 | — | — | WO | disclosed |