Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5991362 | 0.83 | CHRNB2 (0.41) | ALDH1A1AHRCYP3A4CYP2C19 | |
| SCHEMBL8710222 | 0.83 | AHR (0.36) | ALDH1A1AHRCYP3A4CYP2C19 | |
| SCHEMBL5679995 | 0.82 | RARB (0.36) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL10584058 | 0.79 | ACHE (0.37) | SMN1; SMN2HPGDKMT2AMEN1CYP3A4 | |
| SCHEMBL28542806 | 0.79 | CHRNB2 (0.40) | ALDH1A1AHRCYP3A4CYP2C19 | |
| SCHEMBL16415681 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL8517382 | 0.78 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL17816429 | 0.78 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL20535808 | 0.77 | APP (0.34) | ALDH1A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL5074489 | 0.77 | LTA4H (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805132-B1 | Method of producing styrene derivatives | HONSHU CHEMICAL IND (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5763560-A | TREATING BENZALDEHYDE DERIVATIVE WITH ZINC AND ACTIVE CHLORIDE IN AN ORGANIC SOLVENT | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0805132-A1 | Method of producing styrene derivatives | HONSHU CHEMICAL INDUSTRY CO. LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |