Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 5/20 | 0.66 |
| ▸ | FAAH | O00519 | 2/20 | 0.62 |
| ▸ | MGLL | Q99685 | 2/20 | 0.62 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.60 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379447 | 0.90 | FAAH (0.68) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL11278746 | 0.89 | CASP3 (0.74) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL9594067 | 0.88 | FAAH (0.70) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL24836229 | 0.85 | FAAH (0.76) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL24836231 | 0.85 | FAAH (0.81) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL24836228 | 0.84 | FAAH (0.84) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL24690027 | 0.82 | CASP3 (0.66) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL8356552 | 0.82 | CASP3 (0.66) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL8070856 | 0.82 | CASP3 (0.66) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL20350783 | 0.82 | CASP3 (0.66) | CASP3FAAHMGLLKAT2AKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625978-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993016073-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |
| EP-0018100-B1 | SUBSTITUTED AROMATIC BIOLOGICALLY ACTIVE COMPOUND, A PROCESS FOR ITS PREPARATION AND ITS USE AS BIOCIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-01-18 | — | — | EP | disclosed |