Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911325 | 0.96 | TLR8 (0.37) | TLR8THRATHRBHTR2AHTR2C | |
| SCHEMBL4902316 | 0.92 | TLR8 (0.33) | TLR8CYP1A2CYP3A4CYP2C9PKM | |
| SCHEMBL4910196 | 0.78 | TLR8 (0.42) | TLR8HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL4900357 | 0.74 | ALDH1A1 (0.39) | TLR8HTR2AHTR2CHTR1AHTR7 | |
| SCHEMBL5616111 | 0.71 | TLR8 (0.37) | TLR8THRATHRBHTR2AHTR2C | |
| SCHEMBL9373850 | 0.69 | SIGMAR1 (0.31) | THRATHRBHTR2AHTR2CALDH1A1 | |
| SCHEMBL9374550 | 0.69 | KDM4E (0.35) | HTR2AHTR2CHTR7CYP2C19KMT2A | |
| SCHEMBL4902326 | 0.69 | KMT2A (0.32) | CYP1A2CYP3A4CYP2C19ALDH1A1POLB | |
| SCHEMBL4905621 | 0.68 | FYN (0.37) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4904538 | 0.68 | PRKCG (0.34) | TLR8THRBHTR2AHTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289380-B1 | Aryl-heteroaryl-carbinol derivatives having an analgesic activity | ESTEVE LABOR DR (ES) | 1994-12-28 | — | — | EP | claimed |