Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL26695414 | 0.87 | HPGDS (0.54) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL9378512 | 0.85 | MEN1 (0.46) | KDM4EALDH1A1GAAMAPTLMNA | |
| Benzene SCHEMBL28420098 | 0.84 | L3MBTL1 (0.55) | KDM4EALDH1A1GAAMAPTLMNA | |
| Benzene SCHEMBL29089513 | 0.84 | L3MBTL1 (0.55) | KDM4EALDH1A1GAAMAPTLMNA | |
| Benzene SCHEMBL28031566 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL16291133 | 0.81 | L3MBTL1 (0.57) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL3545 | 0.81 | L3MBTL1 (0.57) | KDM4EALDH1A1GAAMAPTLMNA | |
| Alanine SCHEMBL28826574 | 0.81 | ALOX5 (0.49) | KDM4EALDH1A1GAAMAPTLMNA | |
| Benzene SCHEMBL27668000 | 0.80 | LTA4H (0.45) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL25418507 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1GAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353667-B1 | Bithienyl derivatives, process for their preparation, and compositions containing them | BASF AG (DE) | 1994-03-16 | — | — | EP | claimed |
| EP-0353667-A1 | Bithienyl derivatives, process for their preparation, and compositions containing them | BASF Aktiengesellschaft (DE) | 1990-02-07 | — | — | EP | claimed |
| EP-0353667-B1 | Bithienyl derivatives, process for their preparation, and compositions containing them | BASF AG (DE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0353667-A1 | Bithienyl derivatives, process for their preparation, and compositions containing them | BASF Aktiengesellschaft (DE) | 1990-02-07 | — | — | EP | disclosed |